Tags - (20) biophotonics

Department(s)/lab(s): Physics | Photonics Group (Biophotonics) @ Imperial
Summary:

McGinty develops fluorescence lifetime imaging (FLIM) instrumentation, including endoscopic and widefield FLIM systems, for applications in cancer diagnosis and metabolic/functional imaging.

Department(s)/lab(s): Imaging Physics | Menzel Lab @ TU Delft
Summary:

Menzel's group develops computational scattered-light imaging methods, principally 3D Polarized Light Imaging (3D-PLI) and coherent Fourier scatterometry, to reconstruct the crossing-fiber architecture of unstained brain tissue at micrometer resolution without labeling. The lab combines birefringence/diattenuation measurements with finite-difference time-domain light-scattering simulations to push orientation resolution of nerve-fiber tracts beyond what diffusion MRI or standard histology can achieve, and is actively recruiting postdocs to extend the technique to new tissue types and label-free contrast mechanisms.

Department(s)/lab(s): Physics | Photonics Group (Biophotonics) @ Imperial
Summary:

Neil works on advanced optical microscopy techniques including structured-illumination and super-resolved (STED/SIM) imaging, and wavefront-based aberration correction, within Imperial's Photonics/Biophotonics group.

Department(s)/lab(s): Physics | Photonics Group (Biophotonics) @ Imperial
Summary:

Paterson develops adaptive-optics and wavefront-sensing techniques to correct optical aberrations in fluorescence microscopy and imaging through complex/turbid media, improving resolution and depth in biological and biomedical imaging.

Department(s)/lab(s): School of Physics | Reece Optical Trapping and Nanophotonics Laboratory @ UNSW
Summary:

Reece runs UNSW's optical trapping and nanophotonics laboratory. The group combines optical tweezers with spectroscopy and microfluidics to characterise individual nanoparticles and cells: trapping and spectroscopically interrogating plasmonic core-satellite assemblies (with Gooding and Tilley), measuring single-cell mechanics, and building porous-silicon and photonic-crystal resonant structures for label-free biosensing where the analyte shifts a cavity resonance. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — optical trapping is the standard way to hold a nanoscale sensor — including a nanodiamond hosting an NV ensemble at pT/sqrt(Hz) — at a controlled position inside a cell or fluid, and levitated-nanodiamond spin-mechanics is an active field that this group's capabilities map onto almost exactly. Strong practical fit for a bio-oriented quantum sensing candidate.

Department(s)/lab(s): Engineering | Institut Fresnel - MOSAIC Biophotonics Team @ CNRS
Summary:

Rigneault leads the MOSAIC team at Institut Fresnel, developing label-free nonlinear optical microscopy (CARS/SRS) for chemically-specific imaging of lipids and biomolecules in tissue, and pioneering lensless, hair-thin fiber-bundle endoscopes based on wavefront control for minimally invasive deep-tissue and in vivo biological imaging. He holds 17 patents in optical engineering and molecular spectroscopy for the life sciences.

Department(s)/lab(s): Bioengineering | Rowlands Optical Technologies Group @ Imperial
Summary:

Rowlands develops new optical imaging technologies for biology and medicine, including label-free vibrational (coherent Raman) microscopy and computational imaging approaches aimed at faster, higher-resolution biomedical imaging.

Department(s)/lab(s): School of Chemistry | Smith Time-Resolved Spectroscopy and Microspectroscopy Group @ UMelb
Summary:

Smith runs Melbourne's time-resolved fluorescence facility and specialises in the information channels most people throw away: fluorescence lifetime, anisotropy decay and its orientational content, and single-molecule photophysics, applied to organic semiconductors, energy-transfer systems and biological samples. The group builds its own confocal microspectroscopy instrumentation for time-resolved anisotropy imaging and single-molecule detection. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — lifetime- and orientation-resolved fluorescence is the principal orthogonal contrast mechanism to spin-based sensing, and his instrumentation is the natural correlative partner for NV-ensemble DEER/relaxometry experiments at pT/sqrt(Hz) that need an independent optical readout of the same specimen. Preferred attribute present: orientation- and lifetime-resolved methods.

Department(s)/lab(s): Physics | LuMIn - NV & Nanodiamond Biosensing (Treussart) @ ENSPS
Summary:

Treussart uses fluorescent nanodiamonds (NV centres) as photostable bio-probes: intracellular single-particle tracking, nanoscale thermometry/magnetometry, and multimodal biosensing in cells and organisms, alongside super-resolution imaging - a direct NV-ensemble-to-biology bridge. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work is applied here to living cells via nanodiamond probes.

Department(s)/lab(s): Physics & Astronomy | Zheltikov Biophotonics Laboratory @ TAMU
Summary:

Zheltikov integrates NV-diamond magnetometry into photonic-crystal fibers for high-resolution, fiber-delivered magnetic-field imaging and endoscopy, alongside ultrafast biophotonics (multiphoton deep-tissue imaging, SWIR probes) and quantum-light molecular spectroscopy. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work extends NV ensemble sensing into fiberized, in-vivo-compatible geometries.