Aurèle Adam develops THz near-field imaging and spectroscopy. Research: (1) apertureless scattering-type near-field optical microscopy (s-SNOM) at THz frequencies for nanometre spatial resolution imaging of material properties; (2) THz time-domain spectroscopy of quantum materials and condensed matter systems; (3) antenna-coupled detectors and sources for THz near-field imaging. Relevant to quantum material characterisation at the nanoscale.

Marie-Eve Aubin-Tam (Associate Professor, BioNanoscience) uses single-molecule tools to study membrane proteins and cell biophysics. Research: (1) optical tweezers protein unfolding — mechanical unfolding of membrane proteins to probe folding landscape; (2) single-molecule cell biophysics — force spectroscopy on live cells; (3) synthetic biology applications — integrating engineered proteins with biophysical tools.

Daan Brinks develops all-optical electrophysiology tools for neuroscience. His lab engineers genetically-encoded voltage indicators (GEVIs) and combines them with optogenetics to read out and control neural circuit activity. Key directions: (1) engineering bright, fast GEVIs with improved photostability and voltage sensitivity; (2) multiplexed all-optical neural circuit mapping; (3) identifying rare aggressive cancer cells using voltage-sensitive dyes. His voltage imaging approach represents cutting-edge biosensing at the intersection of photonics and neuroscience.

Cees Dekker (Distinguished University Professor, BioNanoscience/Kavli) pioneered solid-state nanopores and single-molecule biophysics. Research: (1) solid-state nanopores for protein sensing and sequencing — detecting individual protein molecules by current blockade; (2) DNA loop extrusion by condensin and cohesin at the single-molecule level; (3) chromatin structure and chromosome organisation with bacteria-on-chip; (4) synthetic cell construction from the bottom up; (5) diagnostic nanopores for neglected diseases. NanoFront 51M€ NWO program leader; 2019 Nature paper on real-time DNA loop extrusion imaging.

Nynke Dekker (Full Professor, BioNanoscience) leads single-molecule biophysics of DNA replication and topology. Research: (1) single-molecule force-fluorescence microscopy — integrated optical tweezers and fluorescence for real-time imaging of replication machinery; (2) DNA topology — supercoiling, gyrase, topoisomerase dynamics with magnetic tweezers; (3) DNA/RNA-processing molecular motors. EMBO member; KNAW member. 2024 integrated force-fluorescence toolbox published.

Marileen Dogterom (Full Professor, BioNanoscience) studies cytoskeleton dynamics and synthetic cell construction. Research: (1) microtubule dynamics — force generation, catastrophe control, and mitotic spindle assembly reconstituted in vitro; (2) cell division reconstitution — building minimal synthetic cells with controlled division; (3) optical tweezers and fluorescence microscopy for force measurement on single cytoskeletal elements. Co-founded BioNanoscience department.

Jian-Rong Gao develops superconducting THz heterodyne detector arrays for radio astronomy and fundamental physics applications. Key work: (1) hot electron bolometer (HEB) and SIS mixer THz receivers operating at sub-mm and THz frequencies; (2) detector arrays for space and ground-based radio telescopes (Herschel, ALMA, and future missions); (3) low-noise amplification at THz frequencies. Joint professor TU Delft and SRON (Netherlands Institute for Space Research).

Hylkje Geertsema uses single-molecule super-resolution fluorescence microscopy (TIRF, SMLM, PALM/STORM) to study DNA replication dynamics. Her lab visualises and quantifies individual replication proteins at replication forks in living cells to understand the kinetics and fidelity of DNA copying. Research focuses on measuring spatiotemporal dynamics of protein assemblies during DNA metabolism with nanometre resolution.

Ghiasi's Quantum Spintronics (QuSpin) Lab studies spin transport and magnetism in 2D and van der Waals materials, and — in close collaboration with the van der Sar group — pioneered a diamond-membrane dry-transfer technique that brings NV-ensemble ensembles into direct nanoscale contact with 2D antiferromagnets (e.g., CrSBr) to quantitatively image monolayer-thickness-dependent magnetic stray fields. This complements the well-established line of NV-ensemble quantum sensing experiments (DEER, NMR, T1-relaxometry) that reach pT/sqrt(Hz)-class sensitivities, extending the toolbox toward mechanical and single-atom/single-spin readout.

Simon Groeblacher's lab probes quantum physics at meso- and macroscopic scales using mechanical motion, rare-earth ion emitters, and superconducting qubits. Key research directions: (1) quantum optomechanics with photonic crystal nano-beam resonators deep in the resolved-sideband regime; (2) silicon defect emitters (rare-earth doped silicon) for quantum network nodes; (3) quantum acoustics experiments coupling mechanical resonators to superconducting qubits. The lab fabricates all devices in-house at Kavli Nanolab and has received NWO Summit Grant for 'Quantum Limits' and QDNL/NWO grant for quantum network nodes.