Dunsby co-invented oblique plane microscopy (a single-objective light-sheet technique) and develops multidimensional fluorescence lifetime and light-sheet imaging instrumentation for live-cell and tissue imaging, applied to cancer diagnostics and cell biology.

Gregor's Laboratory for the Physics of Life builds custom quantitative microscopes (single-objective oblique-plane light-sheet, multicolor live-imaging, single-molecule transcription imaging) to make precision, physics-style measurements of gene expression, morphogen gradients, and chromatin dynamics in living Drosophila embryos and mammalian gastruloids. He is actively recruiting PhD students and postdocs with expertise in super-resolution imaging, nonlinear/ultrafast optics, and instrumentation development.

Menzel's group develops computational scattered-light imaging methods, principally 3D Polarized Light Imaging (3D-PLI) and coherent Fourier scatterometry, to reconstruct the crossing-fiber architecture of unstained brain tissue at micrometer resolution without labeling. The lab combines birefringence/diattenuation measurements with finite-difference time-domain light-scattering simulations to push orientation resolution of nerve-fiber tracts beyond what diffusion MRI or standard histology can achieve, and is actively recruiting postdocs to extend the technique to new tissue types and label-free contrast mechanisms.