Baumberg directs the NanoPhotonics Centre, confining light into sub-nanometre plasmonic 'picocavities' between metal nanostructures to achieve single-molecule-sensitive SERS and study light-matter coupling at the molecular scale. Current work spans low-cost healthcare biosensors, chiral nanophotonics and quantum coherent effects in plasmonic cavities.

Crozier holds a joint Physics/Electrical Engineering chair and runs a nanophotonics laboratory spanning plasmonic and dielectric metasurfaces, on-chip optical trapping and manipulation of nanoparticles and cells, mid-infrared spectroscopy and detection with metasurface-enhanced and colloidal-nanocrystal devices, and light emission from 2D semiconductors. The unifying theme is engineering the local optical density of states to increase the signal available from a very small number of emitters or molecules. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — the plasmonic and dielectric antenna work is the same physics used to raise photon collection efficiency and hence the shot-noise floor of NV-ensemble magnetometers operating at pT/sqrt(Hz). Note: a substantial fraction of the group's output is device fabrication rather than sensitivity-limited measurement, which is a caveat against the stated preference.

De Nijs leads the Physics for Sustainable Chemistry group, studying light-matter interactions at molecular length-scales using plasmonic nanocavities, with applications spanning single-molecule SERS sensing, in-situ electrochemical monitoring, and plasmon-driven photocatalysis for green chemistry (e.g. plastics degradation).

Gardner's group develops infrared and Raman microspectroscopy for biomedical diagnostics and disease sensing. Research directions: (1) FTIR synchrotron microspectroscopy — using Diamond Light Source synchrotron IR beam for high-spatial-resolution chemical mapping of biological tissues for cancer diagnosis; (2) Raman microspectroscopy — label-free chemical imaging of cells and tissue for disease classification using machine-learning chemometrics; (3) SERS probes — developing gold nanoparticle SERS labels for targeted cancer biomarker detection; (4) Breathomics — on-chip photonic sensors for exhaled breath analysis for early disease detection. The infrared and Raman methods provide label-free molecular sensing with potential for quantum-enhanced sensitivity.

Gooding is one of the world's most-cited biosensor scientists (inaugural editor-in-chief of ACS Sensors) and runs a group of over thirty researchers spanning surface chemistry, electrochemistry and nanomedicine. The sensing programme that matters here is the move from ensemble to digital, single-molecule-resolved detection: nanoparticle-tethered electrochemical sensors in which single binding events are counted rather than averaged, nanopore blockade sensors for protein biomarkers such as PSA, amplification-free nucleic-acid detection, and antifouling surface chemistries that make any of this work in real biological fluid. He has a strong commercialisation record (AgaMatrix glucose sensors). Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — his single-molecule-counting philosophy is the biosensing analogue of moving from a pT/sqrt(Hz) NV ensemble to single-spin detection: in both cases the sensitivity gain comes from resolving individual events rather than improving an averaged signal. He is also the obvious collaborator for anyone trying to functionalise a diamond or nanoparticle quantum sensor for a real analyte.

Graham's group develops SERS-based nanoplasmonic sensing platforms for biomedical applications. Research directions: (1) SERS nanogap substrates — engineering colloidal gold and silver nanostructure clusters with reproducible, high-enhancement nanogaps for single-molecule SERS detection; (2) In vivo SERS — intravenous SERS nanotags for tumor imaging and multiplexed biomarker detection in living organisms; (3) Microfluidic SERS — integrating SERS probes in microfluidic channels for continuous monitoring of circulating biomarkers; (4) Quantitative SERS — calibration strategies for absolute analyte quantification for clinical diagnostics. Extreme sensitivity (single-molecule) relevant to quantum-enhanced optical sensing.

Hutchison works on molecular polaritonics: what happens to chemistry when molecular electronic or vibrational transitions are strongly coupled to a confined optical mode in a Fabry-Perot or plasmonic nanocavity. He was among the first to show that vibrational strong coupling modifies ground-state chemical reactivity, and the group continues to probe polariton-modified energy transfer, photochemistry and transport, alongside single-molecule spectroscopy and 2D-material photonics. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — the connection to quantum sensing is the cavity: the same Purcell and collective-coupling physics that concentrates optical density of states around a molecule is what is used to improve photon collection and readout fidelity in NV ensembles operating at pT/sqrt(Hz). This is fundamental light-matter physics with a clear nonclassical-state angle.

Studies molecular and nano-optics, plasmonics, and near-field light-matter interactions, using super-resolution optical imaging to reveal active sites and phase transformations in heterogeneous catalysis and single nanodomains.

Studies photophysics and photochemistry of plasmonic nanomaterials using single-particle optical imaging and ultrafast spectroscopy, with applications to solar energy conversion.

Mulvaney directs the ARC Centre of Excellence in Exciton Science and runs Melbourne's nanoscience laboratory. The group's distinctive capability is single-particle and single-emitter optical spectroscopy: photon-antibunching and blinking statistics from individual quantum dots and perovskite nanocrystals, photothermal and dark-field spectroscopy of individual metal nanoparticles, and the electrochemical control of single-nanocrystal charge state. Applications run from LEDs and solar cells to quantum-dot probes for single-particle tracking in cells. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — his single-emitter photon-statistics measurements share the shot-noise-limited photon-counting methodology of NV-ensemble ODMR readout, and the group's nanocrystal probes are direct competitors/complements to nanodiamond in cellular sensing. Large, well-resourced group.