Gardner's group develops infrared and Raman microspectroscopy for biomedical diagnostics and disease sensing. Research directions: (1) FTIR synchrotron microspectroscopy — using Diamond Light Source synchrotron IR beam for high-spatial-resolution chemical mapping of biological tissues for cancer diagnosis; (2) Raman microspectroscopy — label-free chemical imaging of cells and tissue for disease classification using machine-learning chemometrics; (3) SERS probes — developing gold nanoparticle SERS labels for targeted cancer biomarker detection; (4) Breathomics — on-chip photonic sensors for exhaled breath analysis for early disease detection. The infrared and Raman methods provide label-free molecular sensing with potential for quantum-enhanced sensitivity.