Technique - (14) Surface-enhanced Raman spectroscopy (SERS)

Type: Experimental

Description: Plasmonic nanostructure-enhanced Raman scattering for single-molecule chemical identification and label-free biosensing.

Department(s)/lab(s): School of Physics | Nanophotonics and Electromagnetic Materials Group @ USyd
Summary:

Palomba works on nonlinear nanophotonics and plasmonics: exploiting the extreme field confinement of metallic and hybrid nanostructures to obtain efficient frequency conversion, second- and third-harmonic generation and four-wave mixing in device footprints far smaller than conventional nonlinear optics allows, and integrating these with silicon photonics. The applications the group targets include on-chip nonclassical light generation and nanoscale sensing. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — the plasmonic field-enhancement physics is the same toolkit used to build the nanoantennas that raise photon collection from single NV centres and thereby move single-defect sensing toward the pT/sqrt(Hz) performance of ensembles. Borderline inclusion; the group is device-centred, which cuts against the stated preference.

Department(s)/lab(s): School of Physics | Reece Optical Trapping and Nanophotonics Laboratory @ UNSW
Summary:

Reece runs UNSW's optical trapping and nanophotonics laboratory. The group combines optical tweezers with spectroscopy and microfluidics to characterise individual nanoparticles and cells: trapping and spectroscopically interrogating plasmonic core-satellite assemblies (with Gooding and Tilley), measuring single-cell mechanics, and building porous-silicon and photonic-crystal resonant structures for label-free biosensing where the analyte shifts a cavity resonance. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — optical trapping is the standard way to hold a nanoscale sensor — including a nanodiamond hosting an NV ensemble at pT/sqrt(Hz) — at a controlled position inside a cell or fluid, and levitated-nanodiamond spin-mechanics is an active field that this group's capabilities map onto almost exactly. Strong practical fit for a bio-oriented quantum sensing candidate.

Department(s)/lab(s): Biomedical Engineering | Advanced Spectroscopy Lab @ TAMU
Summary:

Yakovlev develops label-free biomedical imaging: Brillouin micro-spectroscopy of cell/tissue viscoelasticity, impulsive stimulated Brillouin scattering, SERS and coherent-Raman diagnostics, and quantum-enhanced (photon-number-resolving, sub-shot-noise) optical imaging in collaboration with Agarwal/Scully. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work provides the biomedical, quantum-enhanced-imaging bridge for spin-sensor bio-applications.

Department(s)/lab(s): Chemistry / Biomedical Engineering | Yesilkoy Lab @ UWMadison
Summary:

Develops nanophotonic optical biosensors and spectral bioimaging techniques (metasurface/photonic-crystal based) for label-free, high-sensitivity molecular detection.