Description: Label-free vibrational imaging of biological samples using coherent anti-Stokes or stimulated Raman scattering.
Barbosa de Aguiar develops label-free, chemically-selective coherent Raman (CARS/SRS) and computational microscopy β including compressive-sensing-accelerated Raman microspectroscopy and wavefront-shaping through strongly scattering biological tissue β to push spatial and spectral resolution of label-free biomedical imaging, working within Sylvain Gigan's Complex Media Optics team (Photonics, Information & Complexity axis).
Rigneault leads the MOSAIC team at Institut Fresnel, developing label-free nonlinear optical microscopy (CARS/SRS) for chemically-specific imaging of lipids and biomolecules in tissue, and pioneering lensless, hair-thin fiber-bundle endoscopes based on wavefront control for minimally invasive deep-tissue and in vivo biological imaging. He holds 17 patents in optical engineering and molecular spectroscopy for the life sciences.
Rowlands develops new optical imaging technologies for biology and medicine, including label-free vibrational (coherent Raman) microscopy and computational imaging approaches aimed at faster, higher-resolution biomedical imaging.
Scully directs IQSE and pursues foundational quantum optics: quantum coherence effects (lasing without inversion, electromagnetically induced transparency), collective/superradiant emission, quantum-enhanced spectroscopy, and coherent-Raman schemes (FAST CARS) for real-time detection of pathogens and molecular fingerprints. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work sits on the fundamental-light side, providing coherence and superradiance concepts that inform quantum-enhanced magnetometry read-out.
Sokolov develops femtosecond adaptive spectroscopic techniques for coherent Raman (FAST CARS), broadband stochastic laser fields, and quantum-light probes of molecular coherence for standoff chemical/biological sensing and label-free imaging. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work contributes ultrafast coherent-Raman methodology adjacent to spin-based sensing.
Yakovlev develops label-free biomedical imaging: Brillouin micro-spectroscopy of cell/tissue viscoelasticity, impulsive stimulated Brillouin scattering, SERS and coherent-Raman diagnostics, and quantum-enhanced (photon-number-resolving, sub-shot-noise) optical imaging in collaboration with Agarwal/Scully. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work provides the biomedical, quantum-enhanced-imaging bridge for spin-sensor bio-applications.