Barbosa de Aguiar develops label-free, chemically-selective coherent Raman (CARS/SRS) and computational microscopy — including compressive-sensing-accelerated Raman microspectroscopy and wavefront-shaping through strongly scattering biological tissue — to push spatial and spectral resolution of label-free biomedical imaging, working within Sylvain Gigan's Complex Media Optics team (Photonics, Information & Complexity axis).

Sylvain Gigan's PICO (Photonics, Information, and Complexity) group focuses on imaging through and with complex and scattering media. Research: (1) wavefront shaping through scattering media — adaptive optics and transmission matrix approaches for deep-tissue fluorescence imaging; (2) multimode quantum optics through complex media — pushing quantum light through scattering and multi-mode fibres; (3) analogue computing with random optical scattering media. Key for biosensing: deep tissue imaging at high spatial resolution and quantum-enhanced light manipulation.

Sapienza studies light propagation and control in complex/disordered nanophotonic media, using wavefront shaping and transmission-matrix approaches to focus and image through scattering media, with applications to deep-tissue fluorescence imaging and nanophotonic light sources.