Description: Measuring and inverting the optical transmission matrix of biological scattering media to focus light deep in tissue; fluorescence imaging and quantum multimode optics through complex media.
Gigan leads the Optical Imaging group at LKB, pioneering wavefront shaping and computational imaging through scattering media. Research directions: (1) Wavefront shaping / transmission matrix β measuring the ~10^5 optical modes of a scattering sample's transmission matrix to focus and image through highly scattering biological tissues; roadmap on deep tissue imaging (J. Phys. Photonics 2022, lead author); (2) Multimode quantum optics through complex media β spatially multimode squeezed states transmitted through scattering media for quantum-enhanced imaging; (3) Optical computing / AI β using multiple scattering as a physical neural network for reservoir computing and nonlinear machine learning (LightOn spin-off, 2016); (4) Neurophotonics applications β focusing through the skull for deep brain imaging. Two ERC grants (2011, 2017). Optica Fellow. IUF member (2016β2021).
Sylvain Gigan's PICO (Photonics, Information, and Complexity) group focuses on imaging through and with complex and scattering media. Research: (1) wavefront shaping through scattering media β adaptive optics and transmission matrix approaches for deep-tissue fluorescence imaging; (2) multimode quantum optics through complex media β pushing quantum light through scattering and multi-mode fibres; (3) analogue computing with random optical scattering media. Key for biosensing: deep tissue imaging at high spatial resolution and quantum-enhanced light manipulation.
Roberts leads Melbourne's optics group and is a chief investigator in the ARC Centre of Excellence for Transformative Meta-Optical Systems (TMOS). The work is about extracting information that conventional intensity imaging discards: metasurface-encoded point spread functions that recover the full polarisation state or quantitative phase in a single shot, subwavelength structures for edge enhancement and optical computing, and vectorial beam shaping. For a quantum-sensing candidate the relevant hook is that meta-optics is becoming the standard way to miniaturise the optical front end of NV, atomic-vapour and single-molecule sensors, and to add orientational sensitivity to imaging. Positioned against the established body of NV-ensemble quantum sensing work β DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity β her metasurface collection optics and polarisation-resolved detection schemes are being applied to improve photon collection efficiency and orientational discrimination in exactly the NV-ensemble geometries used for pT/sqrt(Hz) magnetometry. Preferred attribute present: orientation-resolved methods that push past standard resolution limits.
Sapienza studies light propagation and control in complex/disordered nanophotonic media, using wavefront shaping and transmission-matrix approaches to focus and image through scattering media, with applications to deep-tissue fluorescence imaging and nanophotonic light sources.