Tags - (6) nanotechnology

Department(s)/lab(s): Chemistry | Ivanov Nanobiotechnology Group @ Imperial
Summary:

Ivanov works on nanotechnology-enabled biosensors and biophysical measurement platforms, including nanopore and microfluidic devices for single-molecule and single-particle biosensing.

Department(s)/lab(s): School of Physics / Institute of Medical Physics | Kuncic Medical Physics and Nanoscale Systems Group @ USyd
Summary:

Kuncic works across medical physics and nanoscale systems: nanoparticle-enhanced radiotherapy and dosimetry (where high-Z nanoparticles act as local dose amplifiers and the physics question is energy deposition at nanometre scales), nanoparticle contrast agents and theranostics, and — separately — neuromorphic nanowire networks as physical computing substrates. The medical-physics thread is the relevant one here: it is about quantifying and imaging what a nanoscale probe does inside tissue. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — the nanoparticle-in-tissue problem she works on is the same delivery-and-quantification problem that determines whether an in-cell nanodiamond sensor operating near the pT/sqrt(Hz) regime reports anything biologically meaningful. Borderline inclusion; a candidate would be bringing quantum sensing to her, not the reverse.

Department(s)/lab(s): School of Physics | Micolich Nanoelectronics Group @ UNSW
Summary:

Micolich works on semiconductor nanowire and organic/polymer nanoelectronic devices, with two strands relevant here: the physics of low-dimensional transport and noise in nanowire transistors, and the use of those devices as transducers at the interface with biological systems, where a nanowire field-effect transistor acts as an extremely local potentiometer sensitive to charge and potential changes at the cell membrane. The group has a strong record in noise spectroscopy — using 1/f and random telegraph noise as a diagnostic rather than a nuisance. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — nanowire FET bioelectronic sensing is the principal electrical competitor to NV-based bio-magnetometry: both aim to read out cellular electrophysiology without patch-clamping, one via magnetic fields at pT/sqrt(Hz), the other via local potential. Borderline inclusion, kept because the bio-interface sensing thread is genuine.

Department(s)/lab(s): School of Chemistry / Bio21 Institute | Mulvaney Nanoscience Laboratory @ UMelb
Summary:

Mulvaney directs the ARC Centre of Excellence in Exciton Science and runs Melbourne's nanoscience laboratory. The group's distinctive capability is single-particle and single-emitter optical spectroscopy: photon-antibunching and blinking statistics from individual quantum dots and perovskite nanocrystals, photothermal and dark-field spectroscopy of individual metal nanoparticles, and the electrochemical control of single-nanocrystal charge state. Applications run from LEDs and solar cells to quantum-dot probes for single-particle tracking in cells. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — his single-emitter photon-statistics measurements share the shot-noise-limited photon-counting methodology of NV-ensemble ODMR readout, and the group's nanocrystal probes are direct competitors/complements to nanodiamond in cellular sensing. Large, well-resourced group.

Department(s)/lab(s): School of Chemistry | Tilley Nanomaterials and Electron Microscopy Group @ UNSW
Summary:

Tilley directs the UNSW Electron Microscope Unit and runs a nanomaterials group whose distinctive capability is in-situ liquid-cell TEM: watching nanoparticle nucleation, growth and catalytic transformation in real time inside the microscope, in liquid, rather than inferring mechanism from before-and-after snapshots. The synthetic side produces magnetic and plasmonic nanoparticles used as biosensor labels and MRI contrast agents, largely in collaboration with Gooding and Reece. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — the group is a supplier and characteriser of the nanoparticle probes that in-cell quantum sensing depends on — including the magnetic-nanoparticle labels whose stray fields a pT/sqrt(Hz) NV sensor would actually detect — and the liquid-cell TEM capability is a rare way to validate what those particles are doing in situ. Borderline inclusion (materials characterisation rather than sensing), kept for the collaborative infrastructure it represents.

Department(s)/lab(s): School of Physics / School of Chemistry | Wickham DNA Nanotechnology Group @ USyd
Summary:

Wickham builds DNA origami nanostructures — programmable, self-assembling scaffolds with nanometre-precision addressability — and uses them as molecular machines, drug-delivery vehicles and, most relevantly, as rulers and probes for single-molecule measurement. DNA origami is the standard platform for DNA-PAINT super-resolution and for positioning fluorophores, nanoparticles or spin labels at defined separations, and her group works on dynamic, reconfigurable devices that respond to biological triggers. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — DNA origami is the leading candidate technology for positioning target molecules at a controlled standoff from a near-surface NV ensemble, which is the central geometric problem in pushing NV nanoscale NMR and DEER from pT/sqrt(Hz) ensembles down to single-molecule sensitivity. Genuinely complementary skill set for a quantum-sensing candidate.