PIs

Associate Professor, University of Sydney 🔗
Status: unreviewed revisit date: None Application status: none LOR status: not_needed
Department(s)/lab(s): School of Physics / School of Chemistry | Wickham DNA Nanotechnology Group @ USyd
Summary:

Wickham builds DNA origami nanostructures — programmable, self-assembling scaffolds with nanometre-precision addressability — and uses them as molecular machines, drug-delivery vehicles and, most relevantly, as rulers and probes for single-molecule measurement. DNA origami is the standard platform for DNA-PAINT super-resolution and for positioning fluorophores, nanoparticles or spin labels at defined separations, and her group works on dynamic, reconfigurable devices that respond to biological triggers. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — DNA origami is the leading candidate technology for positioning target molecules at a controlled standoff from a near-surface NV ensemble, which is the central geometric problem in pushing NV nanoscale NMR and DEER from pT/sqrt(Hz) ensembles down to single-molecule sensitivity. Genuinely complementary skill set for a quantum-sensing candidate.

Created at: July 12, 2026, 1:03 a.m. Updated at: July 12, 2026, 1:03 a.m. Metadata: Fresh 2026-07-11. Primary lab: DNA nanotechnology group, joint School of Physics / School of Chemistry; Sydney Nano Institute.