Research Areas - (169) Quantum Biology / Biosensing

Full path: Biology > Biophysics > Quantum Biology / Biosensing

Department(s)/lab(s): Bioengineering | O'Hare Biosensor Technology Group @ Imperial
Summary:

O'Hare develops electrochemical and optical biosensors for point-of-care and near-patient diagnostics, including miRNA cancer biomarker detection and exhaled-breath-condensate analysis for respiratory and metabolic disease monitoring.

Department(s)/lab(s): Physics & Astronomy – AMOPP | Quantum Biomolecular Processes Group (Olaya-Castro Group) @ UCL
Summary:

Olaya-Castro leads theoretical research on quantum phenomena in biological systems. Research directions: (1) Quantum coherence in photosynthesis — open quantum systems theory for energy transfer in light-harvesting complexes, probing whether quantum coherence provides functional advantage; vibronic coupling models for chromophore-protein complexes; (2) Counting statistics and noise in exciton and charge transfer; (3) Quantum thermodynamics of biomolecular machines — efficiency limits and entropy production in molecular motors; (4) Non-classical features of electronic/vibrational dynamics in chromophores; (5) Connections between quantum information measures and biological function. Collaborates with Bain and Llorente-Garcia on joint experiment/theory biosensing projects. Theoretical work only — no experimental activity.

Department(s)/lab(s): Physics and Astronomy | Nano-optomechanics and Nanophotonics Group (Ou) @ Southampton
Summary:

Bruce (Jun-Yu) Ou's group applies nanomechanics and nanophotonics to quantum sensor manipulation and AI hardware. Research: (1) ultracompact nanomechanical imaging optics for quantum sensor readout; (2) energy-efficient photonic AI hardware; (3) nanomechanical resonators for force sensing at the quantum limit; (4) nanophotonic interfaces to quantum sensors. Relevant to quantum sensor miniaturisation and readout.

Department(s)/lab(s): Physics | LuMIn - Nanoplasmonics & Ultrafast (Palpant) @ ENSPS
Summary:

Palpant (current LuMIn director) studies ultrafast optical response and thermoplasmonics of metal nanoparticles - photothermal nanoscale heat sources and sensors for photonics and biomedicine. Primary appointment CentraleSupelec; based at the ENS Paris-Saclay LuMIn site. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work is adjacent through plasmonic photothermal transduction and sensing.

Department(s)/lab(s): Medical Physics and Biomedical Engineering | UCL Healthcare Biomagnetics Laboratory @ UCL
Summary:

Pankhurst directs the UCL Healthcare Biomagnetics Laboratory, developing magnetic nanoparticles and instrumentation for clinical use: AC-susceptometry-based sentinel-lymph-node localization for breast cancer surgical staging (commercialized as Endomag), magnetic particle imaging, and magnetic hyperthermia therapy. He is a participant in the Q-BIOMED quantum-biomedical-sensing hub, connecting magnetic biosensing with the hub's broader quantum-diagnostics translation effort.

Department(s)/lab(s): Chemistry and Chemical Biology, Physics | Park Group @ Harvard
Summary:

Park's group works at the interface of physics, chemistry, and neuroscience, developing nanowire- and nanoelectrode-based intracellular electrophysiology probes as well as NV-diamond quantum sensing platforms (often in collaboration with Lukin), building on the same NV ensemble quantum-sensing lineage (DEER, nanoscale NMR, T1 relaxometry, pT/√Hz sensitivity) while also pushing nanoscale bioelectronic recording.

Department(s)/lab(s): Physics | Photonics Group (Biophotonics) @ Imperial
Summary:

Paterson develops adaptive-optics and wavefront-sensing techniques to correct optical aberrations in fluorescence microscopy and imaging through complex/turbid media, improving resolution and depth in biological and biomedical imaging.

Department(s)/lab(s): Physics | Quantum Imaging Group (Digistain) @ Imperial
Summary:

Phillips works on quantum imaging (entangled/twin-photon imaging at the quantum limit) and label-free mid-infrared spectroscopic biomedical imaging; he co-founded Digistain, a spin-out applying infrared spectroscopic histopathology to rapid cancer diagnostics.

Department(s)/lab(s): School of Physics | Melbourne Materials Institute Diamond Group (Prawer) @ UMelb
Summary:

Prawer is the founding figure of Melbourne diamond science, spanning colour-centre quantum technology, diamond surface chemistry and — unusually — clinical translation. His group developed the nitrogen-doped ultrananocrystalline diamond electrode arrays used in the Australian diamond bionic eye, a hermetically sealed, chronically implantable retinal stimulator that has been through human implantation; that is a rare example of an exotic-materials sensing/stimulation technology carried into human trials. In parallel the group works on diamond surface termination and functionalisation for near-surface NV sensing, nanodiamond bioconjugation, and diamond as a radiation-hard detector material. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — his surface- and materials-engineering work is precisely what sets the standoff distance, and hence the achievable pT/sqrt(Hz) sensitivity, of near-surface NV ensembles used for DEER and nanoscale NMR. Preferred attribute present: demonstrated human trials with a complex implanted technology.

Department(s)/lab(s): School of Physics | Reece Optical Trapping and Nanophotonics Laboratory @ UNSW
Summary:

Reece runs UNSW's optical trapping and nanophotonics laboratory. The group combines optical tweezers with spectroscopy and microfluidics to characterise individual nanoparticles and cells: trapping and spectroscopically interrogating plasmonic core-satellite assemblies (with Gooding and Tilley), measuring single-cell mechanics, and building porous-silicon and photonic-crystal resonant structures for label-free biosensing where the analyte shifts a cavity resonance. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — optical trapping is the standard way to hold a nanoscale sensor — including a nanodiamond hosting an NV ensemble at pT/sqrt(Hz) — at a controlled position inside a cell or fluid, and levitated-nanodiamond spin-mechanics is an active field that this group's capabilities map onto almost exactly. Strong practical fit for a bio-oriented quantum sensing candidate.