Institutions

Gower Street
London, WC1E 6BT
United Kingdom

Summary: UCLQ coordinates ~120 researchers across a rich range of quantum sensing disciplines. The AMOPP group spans levitated optomechanics (Barker), atomic magnetometry and MIT imaging (Renzoni), femtosecond biosensing (Bain), quantum biology theory (Olaya-Castro), Rydberg atoms (Hogan), and molecular precision physics (Caldwell). The Biological Physics group (Llorente-Garcia) addresses quantum effects in biological systems. UCL is particularly notable for quantum sensing applied to biology, including radical-pair mechanisms, optical magnetometry for MEG, and super-resolution biosensing. The London Centre for Nanotechnology (LCN) provides shared fabrication facilities.

Notes: Top-10 UK research university (QS #9 global). The UCLQ Quantum Science and Technology Institute coordinates ~120 researchers. Key groups in scope: AMOPP group โ€” levitated optomechanics (Barker), atomic magnetometry / MIT imaging (Renzoni), femtosecond biosensing (Bain), quantum biology theory (Olaya-Castro), Rydberg atoms (Hogan), molecular precision physics (Caldwell), quantum optomechanics theory (Monteiro). Biological Physics group (Llorente-Garcia). Member of UK National Quantum Technologies Programme. London Centre for Nanotechnology shares facilities.

Department(s)/lab(s): Physics & Astronomy โ€“ AMOPP | Bain Lab (Femtosecond Laser Spectroscopy and Super-Resolution Biosensing) @ UCL
Summary:

Bain develops advanced laser spectroscopy and super-resolution microscopy techniques for biological applications. Research directions: (1) Femtosecond time-resolved STED (stimulated emission depletion) โ€” combining sub-diffraction spatial resolution with picosecond time resolution to study FRET dynamics in live cells with both spatial and lifetime precision; (2) Time-resolved polarized fluorescence โ€” probing orientation distributions and rotational dynamics of fluorophores; (3) CW STED fluorescence lifetime reconstruction โ€” lower-photodose STED for longer live-cell imaging; (4) Single-molecule FRET to study protein-protein interactions; (5) Single-particle tracking of membrane receptors relevant to viral entry and cancer signaling. Former PhD students include Siรขn Culley (now King's College, SMLM).

Department(s)/lab(s): Physics & Astronomy โ€“ AMOPP | UCL Optomechanics Group (Barker Group) @ UCL
Summary:

Barker leads the UCL Optomechanics Group, focusing on levitated nano/micro-oscillators in vacuum. Research directions: (1) Six-degree-of-freedom cooling โ€” demonstrated simultaneous cavity cooling of all 6 DOF of a levitated nanoparticle (Nature Physics 2023, with Monteiro); (2) Sympathetic cooling of two nanoparticles via Coulomb interaction, squeezing transfer (Phys. Rev. Research 2023); (3) Dark matter searches โ€” levitated nanoparticles as directional dark matter sensors sensitive to nuclear recoil and momentum transfer; QTFP-funded project 'Development of Levitated Quantum Optomechanical Sensors for Dark Matter Detection'; (4) Controlling mode orientations for directional force sensing near the quantum limit; (5) Quantum macroscopic superposition tests. Closely collaborates with Monteiro (theory), Bose (quantum entanglement tests), and Ghag (dark matter).

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Department(s)/lab(s): Department of Imaging Neuroscience | MEG Group, Wellcome Centre for Human Neuroimaging @ UCL
Summary:

Barnes co-developed (with Nottingham's Matt Brookes) OPM-MEG, the first wearable whole-head magnetoencephalography scanner: a helmet of optically-pumped magnetometer quantum sensors (spin-exchange-relaxation-free Rb vapour cells) that lets patients move naturally during a brain scan, inside an actively-nulled magnetically shielded room. His group has validated the system against cryogenic SQUID-MEG, deployed the UK's first paediatric OPM-MEG epilepsy clinic, and extended the technology to spinal-cord recording and naturalistic/VR paradigms -- a direct human-trials application of a quantum sensor whose femtotesla-scale sensitivity is comparable to the pT/sqrt(Hz)-class sensitivity sought from NV-ensemble magnetometry, but achieved with room-temperature atomic vapour cells rather than solid-state spin defects.

Department(s)/lab(s): Physics & Astronomy โ€“ Biophysics | Bell Lab (DNA Nanotechnology and Optical Biosensing) @ UCL
Summary:

Bell's group uses DNA nanotechnology and advanced optical microscopy for single-molecule biosensing. Research directions: (1) DNA-based biosensing โ€” DNA origami structures as programmable biosensing platforms; using structural switching of DNA nanodevices to sense specific biomolecules with single-molecule sensitivity; (2) Super-resolution microscopy with DNA โ€” DNA-PAINT and FRET-based single-molecule localization for mapping molecular architectures in cells; (3) Solid-state nanopores โ€” DNA-threaded through nanopores as a precision biosensor for protein identification and force measurement; (4) Multiplexed single-molecule detection โ€” combining DNA-based sensors with optical readout for parallel biomolecule profiling. New group established at UCL, strong biosensing focus.

Department(s)/lab(s): Physics and Astronomy (AMOPP) | Bose Quantum Information Group @ UCL
Summary:

Bose originated (with Marletto and Vedral) the Bose-Marletto-Vedral (BMV) proposal to witness whether gravity is fundamentally quantum, by testing for gravitationally-induced entanglement between two spatially superposed masses using matter-wave (Stern-Gerlach) interferometry -- an idea he co-developed with quantum-sensing experimentalists including Andrew Geraci (Northwestern) and Peter Barker (UCL). He continues to develop the theory of these quantum-gravity-induced entanglement of masses (QGEM) tests, including decoherence mitigation and multi-qubit witnessing schemes, positioning nanocrystal/levitated-mass interferometry as a route to laboratory tests of quantum gravity.

Department(s)/lab(s): Physics & Astronomy โ€“ Condensed Matter & Materials Physics | Breeze Lab (Solid-State Maser Quantum Sensing) @ UCL
Summary:

Breeze is a senior research fellow at UCL working on room-temperature solid-state masers. Research directions: (1) Pentacene maser โ€” first demonstration of a room-temperature, continuous-wave solid-state maser (Science 2018) using photoexcited triplet-state pentacene in p-terphenyl crystal; achieving amplification with noise temperature near 1 K; (2) Diamond NV maser โ€” developing NV-center-based maser for ultra-low-noise microwave amplification at room temperature, relevant to quantum sensing readout chains; (3) Maser applications โ€” quantum-limited amplification for dark matter searches, MRI signal amplification, and quantum communication repeaters; (4) Spin dynamics โ€” understanding triplet-state dynamics in organic crystals for spin polarization control. Strong relevance to quantum-limited microwave sensing.

Department(s)/lab(s): Physics & Astronomy โ€“ AMOPP | Molecular Quantum Matter Lab (Caldwell Group) @ UCL
Summary:

Caldwell is a Royal Society University Research Fellow establishing the Molecular Quantum Matter Lab at UCL. Research directions: (1) Precision molecular spectroscopy for dark matter and fifth-force searches โ€” measuring isotope shifts in molecular systems to test Standard Model predictions and probe new forces between neutrons and electrons; (2) Quantum control of molecules in external fields โ€” laser cooling, Stark deceleration, and magneto-optical trapping of polar molecules; (3) Molecular beam spectroscopy with frequency comb referencing for ultra-high-precision lineshape measurements. The lab aims to build the most precise molecular spectrometer for BSM physics searches. Actively building the lab and seeking motivated students/postdocs.

Department(s)/lab(s): Physics and Astronomy (AMOPP) | UCL Positronium Spectroscopy Group @ UCL
Summary:

Cassidy's group performs precision optical and microwave spectroscopy of positronium -- a purely leptonic electron-positron atom -- to test bound-state QED to high order and search for new physics, most recently a precision microwave measurement of the 2^3S1 to 2^3P2 fine-structure interval. The group is also developing slow, focused positronium beams toward a laboratory measurement of antimatter's gravitational free-fall, continuing UCL's 50-year history of positron physics.

Department(s)/lab(s): Physics & Astronomy โ€“ AMOPP | Hogan Group (Rydberg Atoms and Molecules) @ UCL
Summary:

Hogan's group studies atoms and molecules in high Rydberg states for precision measurements and quantum sensing. Research directions: (1) Rydberg atom electric field sensing โ€” Rydberg atoms exhibit enormous electric polarizabilities; Stark-map and EIT-based electrometry with sub-mV/cm sensitivity and GHz-range frequency coverage; (2) Rydberg molecule spectroscopy โ€” long-range Rydberg molecules as probes of intermolecular forces; (3) Stark deceleration and trapping of Rydberg atoms/molecules โ€” producing cold samples for precision spectroscopy and scattering experiments; (4) Circular Rydberg states โ€” extremely long-lived states for quantum information storage and sensing. Collaborates on quantum-enhanced sensing of RF/microwave fields.

Department(s)/lab(s): Physics & Astronomy โ€“ Biophysics & London Centre for Nanotechnology | Hoogenboom Lab (High-Speed AFM and Nanoscale Biophysics) @ UCL
Summary:

Hoogenboom leads a biophysics group at UCL specializing in high-speed atomic force microscopy. Research directions: (1) High-speed AFM โ€” imaging conformational dynamics of DNA, proteins (including membrane channels), and chromatin at ms time resolution and sub-nm spatial resolution in aqueous conditions; (2) Nuclear pore complex โ€” mapping transport selectivity and structure of NPCs in native nuclear envelopes using AFM; (3) Antimicrobial mechanisms โ€” imaging membrane disruption by antimicrobial peptides in real time; (4) AFM-based force spectroscopy โ€” measuring single-molecule interaction forces in chromatin and protein assemblies. Strong relevance to biological sensing at the single-molecule level.