Research Areas - (4) OPM Biomagnetism (MEG/MCG)

Full path: Physics > Quantum Sensing > Magnetometry (OPM, SERF, etc.) > OPM Biomagnetism (MEG/MCG)

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Department(s)/lab(s): Department of Imaging Neuroscience | MEG Group, Wellcome Centre for Human Neuroimaging @ UCL
Summary:

Barnes co-developed (with Nottingham's Matt Brookes) OPM-MEG, the first wearable whole-head magnetoencephalography scanner: a helmet of optically-pumped magnetometer quantum sensors (spin-exchange-relaxation-free Rb vapour cells) that lets patients move naturally during a brain scan, inside an actively-nulled magnetically shielded room. His group has validated the system against cryogenic SQUID-MEG, deployed the UK's first paediatric OPM-MEG epilepsy clinic, and extended the technology to spinal-cord recording and naturalistic/VR paradigms -- a direct human-trials application of a quantum sensor whose femtotesla-scale sensitivity is comparable to the pT/sqrt(Hz)-class sensitivity sought from NV-ensemble magnetometry, but achieved with room-temperature atomic vapour cells rather than solid-state spin defects.

Department(s)/lab(s): Melbourne School of Psychological Sciences | Garrido Cognitive Neuroscience and Computational Psychiatry Laboratory @ UMelb
Summary:

Garrido is a computational cognitive neuroscientist โ€” predictive coding, Bayesian brain models, neuroimaging biomarkers for mental health โ€” who was appointed a chief investigator of the ARC Centre of Excellence in Quantum Biotechnology specifically to work with the Melbourne and UQ physics groups on non-invasive quantum-sensor recording of human brain magnetic fields. She is the human-subject and source-reconstruction end of the QUBIC portable-brain-imager programme: her lab supplies the paradigms, the clinical cohorts and the inverse-problem modelling that a diamond- or OPM-based MEG system has to serve. Positioned against the established body of NV-ensemble quantum sensing work โ€” DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity โ€” she is not a sensor developer, but she is the reason the pT/sqrt(Hz)-class magnetometers being built at Melbourne have a human-trials pathway at all. Preferred attributes present in strength: bioelectromagnetism and human trials with novel quantum technologies. Included as a deliberate borderline case โ€” a sensing postdoc would be the physics half of a collaboration with this lab, not a member of it.

Department(s)/lab(s): Physics / Niels Bohr Institute | QUANTOP โ€“ Quantum Optics Center (Polzik Lab) @ UCPH
Summary:

Eugene Polzik's QUANTOP centre uses hot and ultracold atomic spin ensembles and mechanical membranes to generate squeezed, entangled, and single-photon states for quantum sensing and communication. Key directions include: (1) atomic magnetometry and electromagnetic induction imaging for biomedical applications (MEG/MCG-quality sensors); (2) entanglement between a macroscopic mechanical oscillator and an atomic spin ensemble; (3) quantum memory for light; (4) back-action-evading measurement schemes beyond the SQL; and (5) optical preamplification for MRI. QUANTOP heads the Copenhagen Center for Biomedical Quantum Sensing (CBQS), targeting quantum-enhanced disease diagnostics.

Department(s)/lab(s): Physics & Astronomy โ€“ AMOPP | UCL Laser Cooling and Atomic Magnetometry Group (Renzoni Group) @ UCL
Summary:

Renzoni's group is internationally recognized as a pioneer in electromagnetic induction imaging (EMI) with optical atomic magnetometers. Research directions: (1) All-optical 87Rb atomic magnetometer MIT โ€” demonstrated first magnetic induction tomography (MIT) with atomic magnetometers (2013), first EMI of biological tissues below the 1 Smโปยน threshold (Applied Physics Letters 2020), enabling non-invasive cardiac conductivity imaging; (2) Unshielded RF atomic magnetometer operation with general regression neural network auto-optimization; (3) Non-destructive evaluation โ€” industrial corrosion/defect imaging via quantum-sensitive MIT; (4) Sub-Fourier signal processing with nonlinear systems for frequency resolution beyond classical limits. Collaborates with NPL on quantum sensing standards. Applications span medicine (atrial fibrillation), security, and materials inspection.