Technique - (6) DEER (double electron-electron resonance)

Type: Experimental

Description: Pulsed dipolar spectroscopy detecting external spin labels near NV centers; nanoscale distance measurement.

Department(s)/lab(s): Chemistry | Freedman Group @ MIT
Summary:

PREFERRED. Freedman uses synthetic inorganic chemistry to design molecular qubits from the electron spin of paramagnetic coordination complexes (e.g. chromium-centered complexes), giving Angstrom-scale, chemically tunable control over qubit placement and coherence for quantum sensing, communication, and metrology applications, including collaborations targeting dark-matter detection and biological/materials sensing; she directs the Institute-wide Quantum@MIT initiative.

Department(s)/lab(s): School of Physics | Quantum Biotechnology and Diamond Sensing Group (Hollenberg) @ UMelb
Summary:

Hollenberg is the intellectual centre of gravity for diamond quantum sensing in Australia: a theorist-turned-programme-leader whose group develops NV-based quantum probes for biological systems and quantum-computing architectures in silicon and diamond. Current directions include the quantum-probe hyperspectral microscope, in which NV ensembles in a bulk diamond substrate report magnetic and spin-noise contrast from cells cultured directly on the surface; nanodiamond quantum probes for intracellular relaxometry and free-radical detection; theory of decoherence-based sensing (T1 relaxometry as a chemical-specificity channel rather than a nuisance); and single-cell magnetic resonance. He co-leads the Melbourne node of the ARC Centre of Excellence in Quantum Biotechnology (QUBIC) with Simpson and Hinde, which is explicitly chartered to build quantum sensors for live biology, including portable brain imagers. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — his programme is one of the small number worldwide that has carried those ensemble protocols all the way into cell culture and tissue rather than stopping at proof-of-principle magnetometry. Preferred attribute present: the group's emphasis is on sensitivity and biological specificity rather than device fabrication, and QUBIC funding runs to 2030 with recurring postdoc recruitment.

Department(s)/lab(s): PME | Maurer Lab @ UChicago
Summary:

Develops quantum sensing platforms at the biology interface. Core NV-center work: (1) widefield NV magnetic imaging of action potentials in neurons and cardiac tissue; (2) NV-based single-molecule NMR at 14 T resolving molecular structure with single-molecule sensitivity; (3) charge-sensitive shallow NV nanoprobes monitoring real-time cellular electrophysiology; (4) biocompatible diamond surface functionalization enabling multiplexed DNA microarray biosensing; (5) fluorescent-protein spin qubits as biological alternatives to diamond NV (2025 paper, Physics World Top-10 Breakthrough). Runs full NV stack: hot implantation, widefield and confocal ODMR, T1/T2/Hahn echo/DEER/Rabi, automated fitting pipelines. 2026 Sloan Fellow. PhD Lukin/Harvard; postdoc Chu/Stanford. Argonne joint appointment.

Department(s)/lab(s): Chemistry – National Electron Paramagnetic Resonance Facility | National EPR Facility / McInnes Group @ Manchester
Summary:

McInnes leads the National EPR Facility at Manchester (Europe's broadest EPR suite) and researches molecular spin qubits. Research directions: (1) Pulsed EPR spectroscopy of molecular spin systems — Hahn echo, ESEEM, ENDOR, DEER for structural and electronic characterization of inorganic and organometallic complexes; (2) Molecular spin qubits — [Cu(mnt)2]²⁻ and related molecules as candidate qubits; measuring coherence times and investigating decoherence mechanisms; (3) Multi-qubit molecular registers — using exchange interactions for two-qubit gates within a molecule; (4) Magnetic sensing applications — molecular systems for magnetic field sensing below the diffraction limit. Partner of NPL M4Q EPSRC Network for Materials for Quantum.

Department(s)/lab(s): School of Electrical Engineering and Telecommunications | Pla Quantum Spin Control and Sensing Laboratory @ UNSW
Summary:

Pla is the strongest single match in this cohort for a candidate whose background is sensitivity-limited spin detection. His laboratory does inductively-detected electron spin resonance at millikelvin using high-quality-factor superconducting microresonators, read out through Josephson and travelling-wave parametric amplifiers operating at the quantum limit of added noise. The result is ESR sensitivity improved by many orders of magnitude over commercial spectrometers — the group's stated target is single-spin inductive detection — and, in parallel, the development of near-ideal degenerate parametric amplifiers and squeezed microwave states as the readout resource that makes it possible. Applications explicitly include chemistry and biology, where the goal is to do EPR on samples far too small for a conventional spectrometer. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — this is the microwave-inductive route to the same destination: where an NV ensemble reaches pT/sqrt(Hz) by optical readout of many spins, Pla reaches comparable or better spin sensitivity by making the microwave detection chain quantum-limited, and the DEER and dynamical-decoupling sequences are shared verbatim. Preferred attribute present in the strongest form: cutting-edge sensitivity, not device fabrication, is the object.

Department(s)/lab(s): Physics | 3rd Institute of Physics (Wrachtrup Group) @ Stuttgart
Summary:

Wrachtrup is a founder of NV-centre quantum sensing: single-spin and ensemble magnetometry, nanoscale/single-molecule NMR and ESR, nuclear-spin registers, scanning-probe quantum-materials imaging, and programmable diamond nanosensors for chemistry and biology. His group actively recruits postdocs across NV sensing and quantum technology. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work is the reference point, extending DEER/nano-NMR toward single-molecule and cryogenic regimes.