Research Areas - (5) Single-Cell Magnetic Resonance Quantum Sensing

Full path: Physics > Quantum Sensing > NV Centers > Single-Cell Magnetic Resonance Quantum Sensing

Department(s)/lab(s): Electrical & Computer Engineering | Hemmer Quantum Photonics Laboratory @ TAMU
Summary:

Hemmer pioneered NV-diamond spin sensing and super-resolution with spin defects, working on coherent control, photonic integration of NV sensors, and diamond-based magnetometry/imaging bridging physics and engineering. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work is directly in the NV ensemble sensing lineage, emphasizing photonic integration and super-resolution readout.

Department(s)/lab(s): School of Physics | Quantum Biotechnology and Diamond Sensing Group (Hollenberg) @ UMelb
Summary:

Hollenberg is the intellectual centre of gravity for diamond quantum sensing in Australia: a theorist-turned-programme-leader whose group develops NV-based quantum probes for biological systems and quantum-computing architectures in silicon and diamond. Current directions include the quantum-probe hyperspectral microscope, in which NV ensembles in a bulk diamond substrate report magnetic and spin-noise contrast from cells cultured directly on the surface; nanodiamond quantum probes for intracellular relaxometry and free-radical detection; theory of decoherence-based sensing (T1 relaxometry as a chemical-specificity channel rather than a nuisance); and single-cell magnetic resonance. He co-leads the Melbourne node of the ARC Centre of Excellence in Quantum Biotechnology (QUBIC) with Simpson and Hinde, which is explicitly chartered to build quantum sensors for live biology, including portable brain imagers. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — his programme is one of the small number worldwide that has carried those ensemble protocols all the way into cell culture and tissue rather than stopping at proof-of-principle magnetometry. Preferred attribute present: the group's emphasis is on sensitivity and biological specificity rather than device fabrication, and QUBIC funding runs to 2030 with recurring postdoc recruitment.

Tags:
Department(s)/lab(s): Electronic and Electrical Engineering / London Centre for Nanotechnology | Morton Group / UCL Quantum Science and Technology Institute @ UCL
Summary:

Morton directs UCL's Quantum Science and Technology Institute and is Deputy Director of the Q-BIOMED hub. His group manipulates electron and nuclear spins in nanoscale materials (silicon donors, diamond defects) to build quantum sensors, quantum memories, and quantum computing hardware, and within Q-BIOMED is pursuing magnetic-resonance quantum sensing at the single-cell level. He is also a co-founder of the quantum computing spinouts Quantum Motion and Phasecraft.

Department(s)/lab(s): School of Physics | Quantum Imaging and Sensing Laboratory (Simpson) @ UMelb
Summary:

Simpson runs the experimental quantum imaging and sensing laboratory at Melbourne and is the closest match at this institution to a bio-oriented NV sensing postdoc. Two active threads: (i) widefield NV magnetic and spin-relaxation imaging of living cells and tissue, including magnetic imaging of magnetotactic bacteria, cellular free radicals and paramagnetic ion transport, and quantum-probe imaging of neuronal activity; and (ii) engineering Australia's most sensitive diamond vector magnetometer with RMIT and Phasor Innovation, aimed at navigation, underground/undersea sensing and, explicitly, mapping magnetic signals of the human brain in unshielded environments. That second thread is a direct bid at bioelectromagnetism with a quantum sensor. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — Simpson's work is a continuation of exactly that lineage, pushing ensemble DEER/T1-relaxometry contrast mechanisms out of the physics lab and into cell biology and human-scale magnetoencephalography. Preferred attributes present: bioelectromagnetism, human-subject ambitions, sensitivity-limited (not fabrication-limited) programme. QUBIC investigator; recruits postdocs regularly.

Department(s)/lab(s): Physics | 3rd Institute of Physics (Wrachtrup Group) @ Stuttgart
Summary:

Wrachtrup is a founder of NV-centre quantum sensing: single-spin and ensemble magnetometry, nanoscale/single-molecule NMR and ESR, nuclear-spin registers, scanning-probe quantum-materials imaging, and programmable diamond nanosensors for chemistry and biology. His group actively recruits postdocs across NV sensing and quantum technology. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work is the reference point, extending DEER/nano-NMR toward single-molecule and cryogenic regimes.