Smith runs Melbourne's time-resolved fluorescence facility and specialises in the information channels most people throw away: fluorescence lifetime, anisotropy decay and its orientational content, and single-molecule photophysics, applied to organic semiconductors, energy-transfer systems and biological samples. The group builds its own confocal microspectroscopy instrumentation for time-resolved anisotropy imaging and single-molecule detection. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — lifetime- and orientation-resolved fluorescence is the principal orthogonal contrast mechanism to spin-based sensing, and his instrumentation is the natural correlative partner for NV-ensemble DEER/relaxometry experiments at pT/sqrt(Hz) that need an independent optical readout of the same specimen. Preferred attribute present: orientation- and lifetime-resolved methods.

Research centers on manipulating and measuring single molecules with quantum-level precision. Primary platform: ABEL trap (Anti-Brownian ELectrokinetic trap) for single-molecule confinement in free solution without surface tethering, enabling measurement of spectroscopic identity, molecular dynamics, and nanoscale energy transfer at femtomolar concentrations. Also develops orientation-resolved single-molecule imaging and single-molecule FRET for photoadaptation in photosynthetic systems and nanoscale immune cell signaling. QuBBE member. PhD Physics UChicago; joined 2024.

The Stern Group explores fundamental quantum interactions of photons with 2D materials, nano-scale structures, and atoms. Key thrusts: (1) Valley-selective exciton-polaritons in monolayer transition-metal dichalcogenides (MoS₂, MoSe₂, WSe₂) embedded in optical microcavities — hybrid light-matter quasiparticles with valley-selective polarization and cavity-modified dynamics; (2) 2D semiconductor quantum emitters — quantum-dot-like single-photon emitters formed by confinement in TMD nanoribbons and by chemical functionalization/strain engineering of defects; (3) Astrophotonics: collaboration with Argonne National Laboratory and the Australian Astronomical Observatory to design and fabricate silicon ring-resonator photonic circuits for OH sky-background suppression in near-IR astronomical spectrographs; (4) Quantum non-reciprocal photonics in axisymmetric microresonators. Experimental tools: time-resolved spectroscopy, single-photon counting, nanofabrication. DOE Early Career Award; ONR Young Investigator Award; Sloan Research Fellow 2013. Affiliated with Fermilab-Northwestern CAPST.

Pioneers living bioelectronics integrating semiconductor nanostructures with biological systems. Primary directions: (1) silicon nanowire / nanoporous silicon photoelectrochemical interfaces for optical neuromodulation with subcellular spatial resolution; (2) intracellular silicon nanowire probes for recording action potentials from individual organelles; (3) bioinspired flexible mesh electronics for in vivo neural and cardiac interfaces. QuBBE member. 2026 Marian and Stuart Rice Research Award.

Uses ultrafast multidimensional spectroscopy to study structural dynamics of biomolecules. Directions: (1) 2D IR spectroscopy of protein folding, water dynamics, and membrane systems with sub-100-fs time resolution; (2) single-molecule FRET for resolving conformational heterogeneity in proteins and nucleic acids; (3) development of ultrafast mid-IR laser sources and pulse shaping for 2D spectroscopy. Resolves dynamics inaccessible to other methods.

Treussart uses fluorescent nanodiamonds (NV centres) as photostable bio-probes: intracellular single-particle tracking, nanoscale thermometry/magnetometry, and multimodal biosensing in cells and organisms, alongside super-resolution imaging - a direct NV-ensemble-to-biology bridge. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work is applied here to living cells via nanodiamond probes.