Emmanuel Beaurepaire (DR1 CNRS, LOB/École Polytechnique) is a pioneer of multiphoton and harmonic generation deep-tissue microscopy. Research: (1) two-photon excited fluorescence (2PEF) and three-photon deep-tissue brain imaging; (2) second-harmonic generation (SHG) and third-harmonic generation (THG) label-free imaging of collagen, myosin, myelin; (3) multimodal 3-photon light-sheet microscopy with ultrafast lasers; (4) metabolic imaging using FLIM/NADH. Key LOB permanent staff (May 2024). Active collaboration with LCF/Lasers group on ultrafast laser development.
Jacqueline Bloch leads a world-leading group on semiconductor exciton-polariton physics at C2N/Paris-Saclay. Research: (1) polariton condensation and quantum fluids of light — superfluidity, vortices, analogue gravity; (2) topological insulator physics with polaritons; (3) quantum simulation with polariton lattices; (4) fundamental quantum optics of polariton systems. IQUPS co-organiser; C2N head. Key for light-physics sensing relevant to quantum fluids and topological photonics.
Jean-François Roch (Professor at ENS Paris-Saclay, LuMIn) is a world leader in NV-center diamond quantum sensors. Research: (1) NV center magnetometry — scalar and vector magnetic field sensing with ensembles and single NV spins; (2) NV centers in diamond anvil cells for high-pressure magnetometry (world record 240 GPa); (3) joint laboratory (JRL) with Thales R&T on industrial NV quantum sensors; (4) color centres in hBN. IUF Senior Member 2021; Jaffé Prize + Berthelot Medal 2024.
Marie-Claire Schanne-Klein (DR1 CNRS, LOB) specializes in polarized SHG and THG microscopy for structural tissue imaging. Research: (1) polarimetric SHG imaging of collagen fibril organization — molecular orientation mapping; (2) THG microscopy for myelin and red blood cell imaging; (3) structural and functional label-free imaging of connective tissues; (4) multi-scale SHG/THG analysis of biopolymer structure. SHG expert in LOB.
Pascale Senellart's group at C2N develops the world's most efficient and bright quantum dot single-photon sources. Research: (1) high-efficiency single-photon emitters based on semiconductor quantum dots in micropillar cavities — up to 99% efficiency, >98% photon purity; (2) entangled photon pair sources; (3) photonic integrated circuits for quantum information and sensing. Coordinator of Quantum-Saclay ecosystem; co-founder of Quandela (quantum photonics spinoff). Key for quantum sensing with non-classical light.
Chiara Stringari (CRCN CNRS, LOB) develops FLIM-based metabolic imaging. Research: (1) fluorescence lifetime imaging microscopy (FLIM) of NAD(P)H and FAD in live tissue for label-free metabolic mapping; (2) phasor analysis of FLIM data for cellular metabolism states; (3) imaging of myelin dynamics using label-free nonlinear microscopy; (4) metabolic imaging in development and disease. 2025 paper on myelin in Optica.
Willy Supatto (DR2 CNRS, LOB) develops ultrafast two-photon light-sheet microscopy for quantitative in vivo imaging of embryo development and tissue dynamics. Research: (1) two-photon SPIM (light-sheet) for volumetric live imaging in zebrafish embryos; (2) SHG imaging of fibrillar proteins; (3) polarization-THG microscopy of structural anisotropy; (4) photodamage in multiphoton imaging. Part of key LOB team with Beaurepaire.