Description: Phase-retrieval coherent diffractive imaging using synchrotron X-rays for nanoscale biological and materials imaging.
Aeppli leads the Quantum Technologies Group spanning ETH Zurich, EPFL, and PSI. Research directions: (1) Quantum materials imaging — using SLS synchrotron X-rays (including SwissFEL ultrafast pulses) and neutrons at SINQ to image quantum phase transitions, skyrmions, and correlated phases; non-destructive imaging of device structures; (2) Rare-earth quantum magnets and qubits — LiHoF4 as a model quantum system; Er, Pr, and Nd spin qubits in crystals for quantum information and sensing; (3) Semiconductor quantum devices — silicon and germanium nanostructures probed by synchrotron nanoscale X-ray imaging; (4) Van der Waals materials and CDW memory devices. Strong interface with PSI large-scale facilities as unique quantum sensing tools for materials.
Gambardella leads the Magnetism and Interface Physics group at ETH D-MATL. Research directions: (1) Scanning probe magnetometry — using NV-center cantilevers (collaboration with Degen) and magneto-optical Kerr microscopy to image spin textures (skyrmions, domain walls) in thin-film heterostructures with sub-100 nm resolution; (2) Spin-orbit torques — current-induced magnetization switching via interfacial spin-orbit coupling; spin Hall and Rashba effects for spintronic devices; (3) Single-atom magnetism — STM and X-ray absorption for element-specific orbital and spin moments of individual atoms on surfaces; (4) XMCD at synchrotron — quantitative element-specific magnetic spectroscopy. Quantum sensing angle: spin-orbit driven phenomena, high-resolution magnetic imaging.
Gureyev is one of the originators of propagation-based X-ray phase-contrast imaging and the transport-of-intensity phase-retrieval methods that made it practical; his current work concerns the information-theoretic limits of imaging — how signal-to-noise, spatial resolution and radiation dose trade against one another — and the application of those limits to phase-contrast tomography, ptychography and electron microscopy, including biomedical imaging at clinically tolerable dose. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — the shared intellectual core is the noise-resolution-dose triangle: the same estimation-theory framework that sets the pT/sqrt(Hz) floor of an NV ensemble governs how many photons a phase-contrast image needs. Borderline inclusion (X-ray rather than quantum sensing), kept because the technique is explicitly about pushing resolution past conventional limits.
Prof. Jacobsen's group develops novel methods, instruments, and analysis approaches for X-ray nanoscale imaging and applies them to biology and environmental science, using the Advanced Photon Source (APS) at Argonne. Directions: (1) Scanning X-ray fluorescence microscopy (SXFM) for organ-wide and nanoscale elemental mapping of metals (zinc, copper, iron) in biological tissues — central to the NIH-funded QE-Map national resource; imaging how metals regulate cellular functions, synaptic zinc signaling, and neurodegenerative disease; (2) X-ray ptychography and coherent diffractive imaging (CDI) for nanoscale biological imaging beyond the diffraction limit with improved dose efficiency; (3) Development of new algorithms, optics (zone plates), and detector systems to push spatial resolution and dose efficiency in X-ray microscopy — including lensless imaging methods and compressed-sensing reconstruction. Joint appointment at Argonne National Laboratory (Argonne Distinguished Fellow); also involved in QE-Map resource with Kozorovitskiy and Hao Zhang (McCormick).
Quiney (currently Head of School) is a theorist of coherent imaging and relativistic atomic structure. His signature contribution is the theory of X-ray free-electron-laser imaging of single particles, including the modelling of radiation damage and ionisation dynamics during the pulse — the question of whether you can extract structure faster than you destroy it — plus phase-retrieval algorithms for coherent diffractive imaging and ptychography. He also works on relativistic quantum chemistry and atomic structure. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — the connection is methodological rather than physical: his group develops the inverse-problem and photon-budget theory that governs how much information can be pulled out of a shot-noise-limited measurement, which is the same limit that fixes pT/sqrt(Hz) performance in NV ensembles. Theory-first PI with strong coupling to experimental synchrotron/XFEL programmes.