Research centers on manipulating and measuring single molecules with quantum-level precision. Primary platform: ABEL trap (Anti-Brownian ELectrokinetic trap) for single-molecule confinement in free solution without surface tethering, enabling measurement of spectroscopic identity, molecular dynamics, and nanoscale energy transfer at femtomolar concentrations. Also develops orientation-resolved single-molecule imaging and single-molecule FRET for photoadaptation in photosynthetic systems and nanoscale immune cell signaling. QuBBE member. PhD Physics UChicago; joined 2024.

Treussart uses fluorescent nanodiamonds (NV centres) as photostable bio-probes: intracellular single-particle tracking, nanoscale thermometry/magnetometry, and multimodal biosensing in cells and organisms, alongside super-resolution imaging - a direct NV-ensemble-to-biology bridge. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work is applied here to living cells via nanodiamond probes.

Yakovlev develops label-free biomedical imaging: Brillouin micro-spectroscopy of cell/tissue viscoelasticity, impulsive stimulated Brillouin scattering, SERS and coherent-Raman diagnostics, and quantum-enhanced (photon-number-resolving, sub-shot-noise) optical imaging in collaboration with Agarwal/Scully. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work provides the biomedical, quantum-enhanced-imaging bridge for spin-sensor bio-applications.