Booth's Dynamic Optics and Photonics Group develops adaptive-optics methods (deformable mirrors, spatial light modulators) for aberration correction in confocal, two-photon and super-resolution (STORM/STED/SIM) microscopy, enabling higher-fidelity deep-tissue biomedical imaging, alongside applications in ultrafast laser micro-fabrication of photonic devices.
Develops novel optical biomedical imaging technologies (OCT, nonlinear/multiphoton microscopy) for cancer detection, primary-care diagnostics, and neurophotonics, and translates them toward clinical and commercial application.
Bose originated (with Marletto and Vedral) the Bose-Marletto-Vedral (BMV) proposal to witness whether gravity is fundamentally quantum, by testing for gravitationally-induced entanglement between two spatially superposed masses using matter-wave (Stern-Gerlach) interferometry -- an idea he co-developed with quantum-sensing experimentalists including Andrew Geraci (Northwestern) and Peter Barker (UCL). He continues to develop the theory of these quantum-gravity-induced entanglement of masses (QGEM) tests, including decoherence mitigation and multi-qubit witnessing schemes, positioning nanocrystal/levitated-mass interferometry as a route to laboratory tests of quantum gravity.
Bowen leads the CQSE 'Spins and Qubits' theme at Manchester, focusing on organometallic molecular spin qubits for quantum sensing and computing. Research directions: (1) Organometallic La(II) and other rare-earth molecular qudits — designing molecules with multiple accessible spin states (qudits) for encoding quantum information and sensing; (2) Pulsed EPR characterization — Hahn echo, ESEEM, ENDOR at X/W/Q-band to measure coherence times and hyperfine couplings; (3) Integration of molecular qubits into devices — surface deposition and nanoscale addressing; (4) Multi-spin sensing — using exchange-coupled spin pairs as differential sensors of magnetic field gradients. Closely collaborates with Tuna and Winpenny.
PREFERRED. Boyden co-invented optogenetics and expansion microscopy, the latter physically swelling fixed tissue in a hydrogel to achieve nanoscale-resolution imaging on conventional diffraction-limited microscopes; his Synthetic Neurobiology Group continues to push these techniques (expansion revealing, thousandfold expansion microscopy) alongside genetically encoded voltage/activity indicators and brain-wide circuit mapping. The group's Media Lab page notes it is currently accepting new students.
Branton is a pioneer of nanopore sensing, having shown that single DNA/RNA molecules threading through a nanopore produce ionic-current signatures usable for single-molecule sequencing — foundational work underlying the modern solid-state and biological nanopore-sequencing industry, and a direct fit to the biosensing/single-molecule filter criterion.
Brasselet is a CNRS researcher at Institut Fresnel developing polarization- and orientation-resolved fluorescence microscopy, using controlled excitation and detection polarization states to map the 3D orientation and organization of fluorescent probes and biomolecular assemblies (e.g. lipid order, amyloid and cytoskeletal structures) at and beyond the single-molecule level, including recent work on the mathematical foundations of polarimetric microscopy.
Breeze is a senior research fellow at UCL working on room-temperature solid-state masers. Research directions: (1) Pentacene maser — first demonstration of a room-temperature, continuous-wave solid-state maser (Science 2018) using photoexcited triplet-state pentacene in p-terphenyl crystal; achieving amplification with noise temperature near 1 K; (2) Diamond NV maser — developing NV-center-based maser for ultra-low-noise microwave amplification at room temperature, relevant to quantum sensing readout chains; (3) Maser applications — quantum-limited amplification for dark matter searches, MRI signal amplification, and quantum communication repeaters; (4) Spin dynamics — understanding triplet-state dynamics in organic crystals for spin polarization control. Strong relevance to quantum-limited microwave sensing.
Daan Brinks develops all-optical electrophysiology tools for neuroscience. His lab engineers genetically-encoded voltage indicators (GEVIs) and combines them with optogenetics to read out and control neural circuit activity. Key directions: (1) engineering bright, fast GEVIs with improved photostability and voltage sensitivity; (2) multiplexed all-optical neural circuit mapping; (3) identifying rare aggressive cancer cells using voltage-sensitive dyes. His voltage imaging approach represents cutting-edge biosensing at the intersection of photonics and neuroscience.
Bustamante is a founding figure of single-molecule biophysics, using optical and magnetic tweezers to measure the forces and torques generated by molecular motors (RNA polymerase, viral packaging motors, the ribosome) as they act on individual nucleoprotein complexes. The lab continues to push single-molecule force spectroscopy toward sub-piconewton, millisecond resolution to resolve mechanochemical intermediates invisible to bulk assays.