Pioneer of single-molecule/single-nanoparticle surface-enhanced Raman scattering (SERS) and quantum-dot bioconjugate imaging; develops nanoparticle probes for ultrasensitive molecular detection and in vivo tumor imaging.
Nussberger holds the biophysics chair at Stuttgart's Institute of Biomaterials and Biomolecular Systems. The group studies how proteins cross and insert into membranes -- mitochondrial protein translocases (TOM complex), apoptosis-related pore formation -- using single-channel electrophysiology, single-molecule fluorescence and structural methods, and has pushed this into an explicit nanopore/biosensing line: engineered protein and DNA-based pores as single-molecule sensors, including the DNA-origami nanosyringe for directed membrane translocation published with Na Liu's group. Relative to the established NV-ensemble quantum-sensing playbook (DEER, nanoscale NMR, T1 relaxometry at pT/sqrt(Hz) ensemble sensitivity), the relevance is the readout channel: nanopore sensing is the electrical single-molecule counterpart to optical single-molecule detection, and the group's membrane expertise is exactly what an in-cell quantum-sensing project needs when the question becomes how to get the probe across a bilayer.
O'Hare develops electrochemical and optical biosensors for point-of-care and near-patient diagnostics, including miRNA cancer biomarker detection and exhaled-breath-condensate analysis for respiratory and metabolic disease monitoring.
Olaya-Castro leads theoretical research on quantum phenomena in biological systems. Research directions: (1) Quantum coherence in photosynthesis â open quantum systems theory for energy transfer in light-harvesting complexes, probing whether quantum coherence provides functional advantage; vibronic coupling models for chromophore-protein complexes; (2) Counting statistics and noise in exciton and charge transfer; (3) Quantum thermodynamics of biomolecular machines â efficiency limits and entropy production in molecular motors; (4) Non-classical features of electronic/vibrational dynamics in chromophores; (5) Connections between quantum information measures and biological function. Collaborates with Bain and Llorente-Garcia on joint experiment/theory biosensing projects. Theoretical work only â no experimental activity.
Bruce (Jun-Yu) Ou's group applies nanomechanics and nanophotonics to quantum sensor manipulation and AI hardware. Research: (1) ultracompact nanomechanical imaging optics for quantum sensor readout; (2) energy-efficient photonic AI hardware; (3) nanomechanical resonators for force sensing at the quantum limit; (4) nanophotonic interfaces to quantum sensors. Relevant to quantum sensor miniaturisation and readout.
Uses information theory and statistical physics to study neural circuit sensing. Directions: (1) multi-electrode array recording from salamander and mouse retina to map how retinal ganglion cells encode and predict natural visual scenes; (2) information-theoretic quantification of predictive coding strategies in sensory neurons; (3) developing statistical models of population neural codes. Technique focus: high-density multi-electrode arrays as a sensing platform for neural population dynamics. Joint appointment Organismal Biology and Anatomy.
Palpant (current LuMIn director) studies ultrafast optical response and thermoplasmonics of metal nanoparticles - photothermal nanoscale heat sources and sensors for photonics and biomedicine. Primary appointment CentraleSupelec; based at the ENS Paris-Saclay LuMIn site. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work is adjacent through plasmonic photothermal transduction and sensing.
Pankhurst directs the UCL Healthcare Biomagnetics Laboratory, developing magnetic nanoparticles and instrumentation for clinical use: AC-susceptometry-based sentinel-lymph-node localization for breast cancer surgical staging (commercialized as Endomag), magnetic particle imaging, and magnetic hyperthermia therapy. He is a participant in the Q-BIOMED quantum-biomedical-sensing hub, connecting magnetic biosensing with the hub's broader quantum-diagnostics translation effort.
Pantazis directs the Leica Imaging Hub at Imperial and develops advanced live-imaging tools (including novel fluorescent probes and light microscopy methods) to capture the dynamics of embryonic development and disease processes in real time.
Park's group works at the interface of physics, chemistry, and neuroscience, developing nanowire- and nanoelectrode-based intracellular electrophysiology probes as well as NV-diamond quantum sensing platforms (often in collaboration with Lukin), building on the same NV ensemble quantum-sensing lineage (DEER, nanoscale NMR, T1 relaxometry, pT/âHz sensitivity) while also pushing nanoscale bioelectronic recording.