Research Areas - (214) Biophysics

Full path: Biology > Biophysics

Department(s)/lab(s): Bioengineering | Nie Lab @ UIUC
Summary:

Pioneer of single-molecule/single-nanoparticle surface-enhanced Raman scattering (SERS) and quantum-dot bioconjugate imaging; develops nanoparticle probes for ultrasensitive molecular detection and in vivo tumor imaging.

Department(s)/lab(s): Institute of Biomaterials and Biomolecular Systems | Nussberger Lab - Biophysics @ Stuttgart
Summary:

Nussberger holds the biophysics chair at Stuttgart's Institute of Biomaterials and Biomolecular Systems. The group studies how proteins cross and insert into membranes -- mitochondrial protein translocases (TOM complex), apoptosis-related pore formation -- using single-channel electrophysiology, single-molecule fluorescence and structural methods, and has pushed this into an explicit nanopore/biosensing line: engineered protein and DNA-based pores as single-molecule sensors, including the DNA-origami nanosyringe for directed membrane translocation published with Na Liu's group. Relative to the established NV-ensemble quantum-sensing playbook (DEER, nanoscale NMR, T1 relaxometry at pT/sqrt(Hz) ensemble sensitivity), the relevance is the readout channel: nanopore sensing is the electrical single-molecule counterpart to optical single-molecule detection, and the group's membrane expertise is exactly what an in-cell quantum-sensing project needs when the question becomes how to get the probe across a bilayer.

Department(s)/lab(s): Bioengineering | O'Hare Biosensor Technology Group @ Imperial
Summary:

O'Hare develops electrochemical and optical biosensors for point-of-care and near-patient diagnostics, including miRNA cancer biomarker detection and exhaled-breath-condensate analysis for respiratory and metabolic disease monitoring.

Department(s)/lab(s): Physics & Astronomy – AMOPP | Quantum Biomolecular Processes Group (Olaya-Castro Group) @ UCL
Summary:

Olaya-Castro leads theoretical research on quantum phenomena in biological systems. Research directions: (1) Quantum coherence in photosynthesis — open quantum systems theory for energy transfer in light-harvesting complexes, probing whether quantum coherence provides functional advantage; vibronic coupling models for chromophore-protein complexes; (2) Counting statistics and noise in exciton and charge transfer; (3) Quantum thermodynamics of biomolecular machines — efficiency limits and entropy production in molecular motors; (4) Non-classical features of electronic/vibrational dynamics in chromophores; (5) Connections between quantum information measures and biological function. Collaborates with Bain and Llorente-Garcia on joint experiment/theory biosensing projects. Theoretical work only — no experimental activity.

Department(s)/lab(s): Physics and Astronomy | Nano-optomechanics and Nanophotonics Group (Ou) @ Southampton
Summary:

Bruce (Jun-Yu) Ou's group applies nanomechanics and nanophotonics to quantum sensor manipulation and AI hardware. Research: (1) ultracompact nanomechanical imaging optics for quantum sensor readout; (2) energy-efficient photonic AI hardware; (3) nanomechanical resonators for force sensing at the quantum limit; (4) nanophotonic interfaces to quantum sensors. Relevant to quantum sensor miniaturisation and readout.

Department(s)/lab(s): Physics | Palmer Lab @ UChicago
Summary:

Uses information theory and statistical physics to study neural circuit sensing. Directions: (1) multi-electrode array recording from salamander and mouse retina to map how retinal ganglion cells encode and predict natural visual scenes; (2) information-theoretic quantification of predictive coding strategies in sensory neurons; (3) developing statistical models of population neural codes. Technique focus: high-density multi-electrode arrays as a sensing platform for neural population dynamics. Joint appointment Organismal Biology and Anatomy.

Department(s)/lab(s): Physics | LuMIn - Nanoplasmonics & Ultrafast (Palpant) @ ENSPS
Summary:

Palpant (current LuMIn director) studies ultrafast optical response and thermoplasmonics of metal nanoparticles - photothermal nanoscale heat sources and sensors for photonics and biomedicine. Primary appointment CentraleSupelec; based at the ENS Paris-Saclay LuMIn site. In the broader landscape of NV-centre ensemble quantum sensing (DEER, nano-NMR, T1 relaxometry) operating near pT/sqrt(Hz) sensitivity, this work is adjacent through plasmonic photothermal transduction and sensing.

Department(s)/lab(s): Medical Physics and Biomedical Engineering | UCL Healthcare Biomagnetics Laboratory @ UCL
Summary:

Pankhurst directs the UCL Healthcare Biomagnetics Laboratory, developing magnetic nanoparticles and instrumentation for clinical use: AC-susceptometry-based sentinel-lymph-node localization for breast cancer surgical staging (commercialized as Endomag), magnetic particle imaging, and magnetic hyperthermia therapy. He is a participant in the Q-BIOMED quantum-biomedical-sensing hub, connecting magnetic biosensing with the hub's broader quantum-diagnostics translation effort.

Research areas:
Department(s)/lab(s): Bioengineering | Pantazis Advanced Bioimaging Group / Leica Imaging Hub @ Imperial
Summary:

Pantazis directs the Leica Imaging Hub at Imperial and develops advanced live-imaging tools (including novel fluorescent probes and light microscopy methods) to capture the dynamics of embryonic development and disease processes in real time.

Department(s)/lab(s): Chemistry and Chemical Biology, Physics | Park Group @ Harvard
Summary:

Park's group works at the interface of physics, chemistry, and neuroscience, developing nanowire- and nanoelectrode-based intracellular electrophysiology probes as well as NV-diamond quantum sensing platforms (often in collaboration with Lukin), building on the same NV ensemble quantum-sensing lineage (DEER, nanoscale NMR, T1 relaxometry, pT/√Hz sensitivity) while also pushing nanoscale bioelectronic recording.