Develops mass spectrometry-based imaging and proteomics technologies, including integration of tissue expansion microscopy with mass spectrometry imaging to achieve higher spatial resolution molecular maps of tissues such as tumors and brain.

Murray develops mid-infrared photonic sources and detectors and combines mid-IR spectroscopy with mass-spectrometry imaging to provide complementary optical and biochemical maps of tissue for biomedical sensing.

Develops single-cell and mass-spectrometry imaging technologies to discover and map neuropeptides and other small-molecule signaling agents involved in cell-cell communication.

Zare's group develops laser and mass-spectrometric methods -- including single-cell mass spectrometry and mass spectrometry imaging of neuropeptides -- to chemically profile individual cells and tissue sections with high molecular specificity, alongside long-standing work in microdroplet and chiral-selective chemistry.