Description: Genetically encoded peroxidase/biotin-ligase reporters that biotinylate proximal proteins for spatial proteomic and EM contrast mapping.
Ting's lab invented proximity-dependent enzymatic labeling technologies (APEX, TurboID) that map the spatial proteome and transcriptome of living cells with organelle-level resolution, and develops genetically encoded fluorescent/voltage biosensors -- engineering biology's own molecular machinery into quantitative optical reporters.