Prentiss's group works on cold-atom light-pulse interferometry for compact, potentially fieldable inertial sensors (gravimeters/gyroscopes), alongside a parallel biophysics program using optical tweezers and single-molecule methods to study DNA and cell mechanics. The atom-interferometric sensing work is squarely in the quantum-sensing gravimetry/inertial-navigation tradition alongside cold-atom-gradiometer and atom-chip clock efforts elsewhere in the field.