De Sterke is a theorist-experimentalist of nonlinear and structured photonics. The group's signature recent contribution is the pure-quartic soliton: by engineering the dispersion of a waveguide so that the group velocity depends on the third power of frequency, they produce solitons with a different energy-width scaling from conventional ones, with direct consequences for mode-locked laser and frequency-comb design. The group also works on topological and non-Hermitian photonics and on THz metamaterials. Positioned against the established body of NV-ensemble quantum sensing work — DEER, nanoscale NMR and T1 relaxometry protocols operating at pT/sqrt(Hz) field sensitivity — the relevance is to the light side of the search rather than the spin side: dispersion-engineered comb and soliton sources are the local oscillators and reference clocks that any optical readout of a pT/sqrt(Hz) sensor ultimately depends on. Borderline inclusion; kept for the fundamental-light-physics criterion.

Studies computational classical and quantum electrodynamics, quantum optics, topological photonics, and integrated photonics, including radiative cooling and visual perception applications.